Structural Basis for Dual-Inhibition Mechanism of a Non-Classical Kazal-Type Serine Protease Inhibitor from Horseshoe Crab in Complex with Subtilisin

Serine proteases play a crucial role in host-pathogen interactions. In the innate immune system of invertebrates, multi-domain protease inhibitors are important for the regulation of host-pathogen interactions and antimicrobial activities. Serine protease inhibitors, 9.3-kDa CrSPI isoforms 1 and 2,...

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Detalles Bibliográficos
Autores principales: Shenoy, Rajesh T., Thangamani, Saravanan, Velazquez-Campoy, Adrian, Ho, Bow, Ding, Jeak Ling, Sivaraman, J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082530/
https://www.ncbi.nlm.nih.gov/pubmed/21541315
http://dx.doi.org/10.1371/journal.pone.0018838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082530/
https://www.ncbi.nlm.nih.gov/pubmed/21541315
http://dx.doi.org/10.1371/journal.pone.0018838

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