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A Requirement of TolC and MDR Efflux Pumps for Acid Adaptation and GadAB Induction in Escherichia coli

BACKGROUND: The TolC outer membrane channel is a key component of several multidrug resistance (MDR) efflux pumps driven by H(+) transport in Escherichia coli. While tolC expression is under the regulation of the EvgA-Gad acid resistance regulon, the role of TolC in growth at low pH and extreme-acid...

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Detalles Bibliográficos
Autores principales: Deininger, Kari N. W., Horikawa, Akina, Kitko, Ryan D., Tatsumi, Ryoko, Rosner, Judah L., Wachi, Masaaki, Slonczewski, Joan L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082540/
https://www.ncbi.nlm.nih.gov/pubmed/21541325
http://dx.doi.org/10.1371/journal.pone.0018960