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A Requirement of TolC and MDR Efflux Pumps for Acid Adaptation and GadAB Induction in Escherichia coli
BACKGROUND: The TolC outer membrane channel is a key component of several multidrug resistance (MDR) efflux pumps driven by H(+) transport in Escherichia coli. While tolC expression is under the regulation of the EvgA-Gad acid resistance regulon, the role of TolC in growth at low pH and extreme-acid...
Autores principales: | Deininger, Kari N. W., Horikawa, Akina, Kitko, Ryan D., Tatsumi, Ryoko, Rosner, Judah L., Wachi, Masaaki, Slonczewski, Joan L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082540/ https://www.ncbi.nlm.nih.gov/pubmed/21541325 http://dx.doi.org/10.1371/journal.pone.0018960 |
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