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hHGF Overexpression in Myoblast Sheets Enhances Their Angiogenic Potential in Rat Chronic Heart Failure

After severe myocardial infarction (MI), heart failure results from ischemia, fibrosis, and remodeling. A promising therapy to enhance cardiac function and induce therapeutic angiogenesis via a paracrine mechanism in MI is myoblast sheet transplantation. We hypothesized that in a rat model of MI-ind...

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Detalles Bibliográficos
Autores principales: Siltanen, Antti, Kitabayashi, Katsukiyo, Lakkisto, Päivi, Mäkelä, Johanna, Pätilä, Tommi, Ono, Masamichi, Tikkanen, Ilkka, Sawa, Yoshiki, Kankuri, Esko, Harjula, Ari
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082550/
https://www.ncbi.nlm.nih.gov/pubmed/21541335
http://dx.doi.org/10.1371/journal.pone.0019161