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Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats

The cofactor nicotinamide adenine dinucleotide (NAD+) has emerged as a key regulator of metabolism, stress resistance and longevity. Apart from its role as an important redox carrier, NAD+ also serves as the sole substrate for NAD-dependent enzymes, including poly(ADP-ribose) polymerase (PARP), an i...

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Detalles Bibliográficos
Autores principales: Braidy, Nady, Guillemin, Gilles J., Mansour, Hussein, Chan-Ling, Tailoi, Poljak, Anne, Grant, Ross
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082551/
https://www.ncbi.nlm.nih.gov/pubmed/21541336
http://dx.doi.org/10.1371/journal.pone.0019194