Expression of a Dominant Negative CELF Protein In Vivo Leads to Altered Muscle Organization, Fiber Size, and Subtype

BACKGROUND: CUG-BP and ETR-3-like factor (CELF) proteins regulate tissue- and developmental stage-specific alternative splicing in striated muscle. We previously demonstrated that heart muscle-specific expression of a nuclear dominant negative CELF protein in transgenic mice (MHC-CELFΔ) effectively...

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Detalles Bibliográficos
Autores principales: Berger, Dara S., Moyer, Michelle, Kliment, Gregory M., van Lunteren, Erik, Ladd, Andrea N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082560/
https://www.ncbi.nlm.nih.gov/pubmed/21541285
http://dx.doi.org/10.1371/journal.pone.0019274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082560/
https://www.ncbi.nlm.nih.gov/pubmed/21541285
http://dx.doi.org/10.1371/journal.pone.0019274

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