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Differentiation Generates Paracrine Cell Pairs That Maintain Basaloid Mouse Mammary Tumors: Proof of Concept

There is a paradox offered up by the cancer stem cell hypothesis. How are the mixed populations that are characteristic of heterogeneous solid tumors maintained at constant proportion, given their high, and different, mitotic indices? In this study, we evaluate a well-characterized mouse model of hu...

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Detalles Bibliográficos
Autores principales: Kim, Soyoung, Goel, Shruti, Alexander, Caroline M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082567/
https://www.ncbi.nlm.nih.gov/pubmed/21541292
http://dx.doi.org/10.1371/journal.pone.0019310