The role of population PK–PD modelling in paediatric clinical research

Children differ from adults in their response to drugs. While this may be the result of changes in dose exposure (pharmacokinetics [PK]) and/or exposure response (pharmacodynamics [PD]) relationships, the magnitude of these changes may not be solely reflected by differences in body weight. As a cons...

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Detalles Bibliográficos
Autores principales: De Cock, Roosmarijn F. W., Piana, Chiara, Krekels, Elke H. J., Danhof, Meindert, Allegaert, Karel, Knibbe, Catherijne A. J.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082690/
https://www.ncbi.nlm.nih.gov/pubmed/20340012
http://dx.doi.org/10.1007/s00228-009-0782-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082690/
https://www.ncbi.nlm.nih.gov/pubmed/20340012
http://dx.doi.org/10.1007/s00228-009-0782-9

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