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Probing rate of YMDD motif mutant in lamivudine treatment of Iranian patients with chronic hepatitis B virus infection

BACKGROUND: Lamivudine is an analog nucleoside used for the treatment of chronic hepatitis B virus (CHV) infection. Studies showed that prolonged therapy could induce lamivudine resistance hepatitis B virus (HBV) variants (YMDD motif). In this study, the rate of YMDD motif mutants is determined in l...

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Detalles Bibliográficos
Autores principales: Ghandehari, Freshte, Pourazar, Abasali, Zadeh, Mehrnaz Shanehsaz, Tajedin, Nahid
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082713/
https://www.ncbi.nlm.nih.gov/pubmed/21572712
http://dx.doi.org/10.4103/0973-6247.75982