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Review of cellular and molecular pathways linking thrombosis and innate immune system during sepsis

Cellular and molecular pathways link thrombosis and innate immune system during sepsis. Extrinsic pathway activation of protease thrombin through FVIIa and tissue factor (TF) in sepsis help activate its endothelial cell (EC) membrane Protease Activated Receptor 1 (PAR-1). Thrombin adjusts the EC cyc...

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Detalles Bibliográficos
Autor principal: Konecny, Filip A.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082833/
https://www.ncbi.nlm.nih.gov/pubmed/21526108