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Mechanistic insights into an engineered riboswitch: a switching element which confers riboswitch activity

While many different RNA aptamers have been identified that bind to a plethora of small molecules only very few are capable of acting as engineered riboswitches. Even for aptamers binding the same ligand large differences in their regulatory potential were observed. We address here the molecular bas...

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Detalles Bibliográficos
Autores principales: Weigand, Julia E., Schmidtke, Sina R., Will, Tristan J., Duchardt-Ferner, Elke, Hammann, Christian, Wöhnert, Jens, Suess, Beatrix
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082870/
https://www.ncbi.nlm.nih.gov/pubmed/21149263
http://dx.doi.org/10.1093/nar/gkq946