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A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA

Recently, 5-hydroxymethylcytosine (5hmC) was identified in mammalian genomic DNA. The biological role of this modification remains unclear; however, identifying the genomic location of this modified base will assist in elucidating its function. We describe a method for the rapid and inexpensive iden...

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Detalles Bibliográficos
Autores principales: Robertson, Adam B., Dahl, John A., Vågbø, Cathrine B., Tripathi, Pankaj, Krokan, Hans E., Klungland, Arne
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082876/
https://www.ncbi.nlm.nih.gov/pubmed/21300643
http://dx.doi.org/10.1093/nar/gkr051