Expression of CD44 3′-untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis

The non-coding 3′-untranslated region (UTR) plays an important role in the regulation of microRNA (miRNA) functions, since it can bind and inactivate multiple miRNAs. Here, we show the 3′-UTR of CD44 is able to antagonize cytoplasmic miRNAs, and result in the increased translation of CD44 and downst...

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Detalles Bibliográficos
Autores principales: Jeyapalan, Zina, Deng, Zhaoqun, Shatseva, Tatiana, Fang, Ling, He, Chengyan, Yang, Burton B.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082902/
https://www.ncbi.nlm.nih.gov/pubmed/21149267
http://dx.doi.org/10.1093/nar/gkq1003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082902/
https://www.ncbi.nlm.nih.gov/pubmed/21149267
http://dx.doi.org/10.1093/nar/gkq1003

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