Rescue of non-sense mutated p53 tumor suppressor gene by aminoglycosides

Mutation-based treatments are a new development in genetic medicine, in which the nature of the mutation dictates the therapeutic strategy. Interest has recently focused on diseases caused by premature termination codons (PTCs). Drugs inducing the readthrough of these PTCs restore the production of...

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Detalles Bibliográficos
Autores principales: Floquet, Célia, Deforges, Jules, Rousset, Jean-Pierre, Bidou, Laure
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082906/
https://www.ncbi.nlm.nih.gov/pubmed/21149266
http://dx.doi.org/10.1093/nar/gkq1277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082906/
https://www.ncbi.nlm.nih.gov/pubmed/21149266
http://dx.doi.org/10.1093/nar/gkq1277

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