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Rescue of non-sense mutated p53 tumor suppressor gene by aminoglycosides
Mutation-based treatments are a new development in genetic medicine, in which the nature of the mutation dictates the therapeutic strategy. Interest has recently focused on diseases caused by premature termination codons (PTCs). Drugs inducing the readthrough of these PTCs restore the production of...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082906/ https://www.ncbi.nlm.nih.gov/pubmed/21149266 http://dx.doi.org/10.1093/nar/gkq1277 |