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Mutations in the intersubunit bridge regions of 16S rRNA affect decoding and subunit–subunit interactions on the 70S ribosome

The small and large subunits of the ribosome are held together by a series of bridges, involving RNA–RNA, RNA–protein and protein–protein interactions. Some 12 bridges have been described for the Escherichia coli 70S ribosome. In this work, we have targeted for mutagenesis, some of the 16S rRNA resi...

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Detalles Bibliográficos
Autores principales: Sun, Qing, Vila-Sanjurjo, Antón, O’Connor, Michael
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082907/
https://www.ncbi.nlm.nih.gov/pubmed/21138965
http://dx.doi.org/10.1093/nar/gkq1253