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SUMO modification of cell surface Kv2.1 potassium channels regulates the activity of rat hippocampal neurons

Voltage-gated Kv2.1 potassium channels are important in the brain for determining activity-dependent excitability. Small ubiquitin-like modifier proteins (SUMOs) regulate function through reversible, enzyme-mediated conjugation to target lysine(s). Here, sumoylation of Kv2.1 in hippocampal neurons i...

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Detalles Bibliográficos
Autores principales: Plant, Leigh D., Dowdell, Evan J., Dementieva, Irina S., Marks, Jeremy D., Goldstein, Steve A.N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082930/
https://www.ncbi.nlm.nih.gov/pubmed/21518833
http://dx.doi.org/10.1085/jgp.201110604