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SUMO modification of cell surface Kv2.1 potassium channels regulates the activity of rat hippocampal neurons
Voltage-gated Kv2.1 potassium channels are important in the brain for determining activity-dependent excitability. Small ubiquitin-like modifier proteins (SUMOs) regulate function through reversible, enzyme-mediated conjugation to target lysine(s). Here, sumoylation of Kv2.1 in hippocampal neurons i...
Autores principales: | Plant, Leigh D., Dowdell, Evan J., Dementieva, Irina S., Marks, Jeremy D., Goldstein, Steve A.N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082930/ https://www.ncbi.nlm.nih.gov/pubmed/21518833 http://dx.doi.org/10.1085/jgp.201110604 |
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