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Functional Model of Metabolite Gating by Human Voltage-Dependent Anion Channel 2

[Image: see text] Voltage-dependent anion channels (VDACs) are critical regulators of outer mitochondrial membrane permeability in eukaryotic cells. VDACs have also been postulated to regulate cell death mechanisms. Erastin, a small molecule quinazolinone that is selectively lethal to tumor cells ex...

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Detalles Bibliográficos
Autores principales: Bauer, Andras J., Gieschler, Simone, Lemberg, Kathryn M., McDermott, Ann E., Stockwell, Brent R.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082971/
https://www.ncbi.nlm.nih.gov/pubmed/21425834
http://dx.doi.org/10.1021/bi2003247