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Complex modulation of androgen responsive gene expression by methoxyacetic acid

BACKGROUND: Optimal androgen signaling is critical for testicular development and spermatogenesis. Methoxyacetic acid (MAA), the primary active metabolite of the industrial chemical ethylene glycol monomethyl ether, disrupts spermatogenesis and causes testicular atrophy. Transcriptional trans-activa...

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Detalles Bibliográficos
Autores principales: Bagchi, Gargi, Zhang, Yijing, Stanley, Kerri A, Waxman, David J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083340/
https://www.ncbi.nlm.nih.gov/pubmed/21453523
http://dx.doi.org/10.1186/1477-7827-9-42