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Complex modulation of androgen responsive gene expression by methoxyacetic acid
BACKGROUND: Optimal androgen signaling is critical for testicular development and spermatogenesis. Methoxyacetic acid (MAA), the primary active metabolite of the industrial chemical ethylene glycol monomethyl ether, disrupts spermatogenesis and causes testicular atrophy. Transcriptional trans-activa...
Autores principales: | Bagchi, Gargi, Zhang, Yijing, Stanley, Kerri A, Waxman, David J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083340/ https://www.ncbi.nlm.nih.gov/pubmed/21453523 http://dx.doi.org/10.1186/1477-7827-9-42 |
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