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Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin
Survivin (BIRC5), a member of the inhibitor of apoptosis protein (IAP) family that inhibits caspases and blocks cell death is highly expressed in cancer and is associated with a poorer clinical outcome. Functioning simultaneously during cell division and apoptosis inhibition, survivin plays a pivota...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083377/ https://www.ncbi.nlm.nih.gov/pubmed/21470426 http://dx.doi.org/10.1186/1476-4598-10-35 |