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Region-Specific Expression of Mitochondrial Complex I Genes during Murine Brain Development

Mutations in the nuclear encoded subunits of mitochondrial complex I (NADH:ubiquinone oxidoreductase) may cause circumscribed cerebral lesions ranging from degeneration of the striatal and brainstem gray matter (Leigh syndrome) to leukodystrophy. We hypothesized that such pattern of regional patholo...

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Detalles Bibliográficos
Autores principales: Wirtz, Stefanie, Schuelke, Markus
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083399/
https://www.ncbi.nlm.nih.gov/pubmed/21556144
http://dx.doi.org/10.1371/journal.pone.0018897