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Performance of Cpred/Cobs concentration ratios as a metric reflecting adherence to antidepressant drug therapy

BACKGROUND: Nonadherence is very common among subjects undergoing pharmacotherapy for schizophrenia and depression. This study aimed to evaluate the performance of the ratio of the nonlinear mixed effects pharmacokinetic model predicted concentration to observed drug concentration (ratio of populati...

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Detalles Bibliográficos
Autores principales: Feng, Yan, Gastonguay, Marc R, Pollock, Bruce G, Frank, Ellen, Kepple, Gail H, Bies, Robert R
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083985/
https://www.ncbi.nlm.nih.gov/pubmed/21552314
http://dx.doi.org/10.2147/NDT.S15921