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Performance of Cpred/Cobs concentration ratios as a metric reflecting adherence to antidepressant drug therapy
BACKGROUND: Nonadherence is very common among subjects undergoing pharmacotherapy for schizophrenia and depression. This study aimed to evaluate the performance of the ratio of the nonlinear mixed effects pharmacokinetic model predicted concentration to observed drug concentration (ratio of populati...
Autores principales: | Feng, Yan, Gastonguay, Marc R, Pollock, Bruce G, Frank, Ellen, Kepple, Gail H, Bies, Robert R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083985/ https://www.ncbi.nlm.nih.gov/pubmed/21552314 http://dx.doi.org/10.2147/NDT.S15921 |
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