In vivo monitoring of fetoplacental Vegfr2 gene activity in a murine pregnancy model using a Vegfr2-luc reporter gene and bioluminescent imaging

BACKGROUND: Vascular endothelial growth factor receptor-2 (VEGFR2) plays a pivotal role in angiogenesis by eliciting vascular endothelial cell growth when bound to VEGF, a powerful pro-angiogenic ligand. While Vegf and Vegfr2 are expressed throughout gestation, the latter third of gestation in mice...

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Detalles Bibliográficos
Autores principales: Greene, Jonathan M, Dunaway, Chad W, Bowers, Susan D, Rude, Brian J, Feugang, Jean M, Ryan, Peter L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084164/
https://www.ncbi.nlm.nih.gov/pubmed/21496302
http://dx.doi.org/10.1186/1477-7827-9-51

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084164/
https://www.ncbi.nlm.nih.gov/pubmed/21496302
http://dx.doi.org/10.1186/1477-7827-9-51

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