Completion of Hepatitis C Virus Replication Cycle in Heterokaryons Excludes Dominant Restrictions in Human Non-liver and Mouse Liver Cell Lines

Hepatitis C virus (HCV) is hepatotropic and only infects humans and chimpanzees. Consequently, an immunocompetent small animal model is lacking. The restricted tropism of HCV likely reflects specific host factor requirements. We investigated if dominant restriction factors expressed in non-liver or...

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Detalles Bibliográficos
Autores principales: Frentzen, Anne, Hüging, Kathrin, Bitzegeio, Julia, Friesland, Martina, Haid, Sibylle, Gentzsch, Juliane, Hoffmann, Markus, Lindemann, Dirk, Zimmer, Gert, Zielecki, Florian, Weber, Friedemann, Steinmann, Eike, Pietschmann, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084199/
https://www.ncbi.nlm.nih.gov/pubmed/21552323
http://dx.doi.org/10.1371/journal.ppat.1002029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084199/
https://www.ncbi.nlm.nih.gov/pubmed/21552323
http://dx.doi.org/10.1371/journal.ppat.1002029

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