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A Mathematical Framework for Estimating Pathogen Transmission Fitness and Inoculum Size Using Data from a Competitive Mixtures Animal Model

We present a method to measure the relative transmissibility (“transmission fitness”) of one strain of a pathogen compared to another. The model is applied to data from “competitive mixtures” experiments in which animals are co-infected with a mixture of two strains. We observe the mixture in each a...

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Detalles Bibliográficos
Autores principales: McCaw, James M., Arinaminpathy, Nimalan, Hurt, Aeron C., McVernon, Jodie, McLean, Angela R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084214/
https://www.ncbi.nlm.nih.gov/pubmed/21552544
http://dx.doi.org/10.1371/journal.pcbi.1002026