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A Mathematical Framework for Estimating Pathogen Transmission Fitness and Inoculum Size Using Data from a Competitive Mixtures Animal Model
We present a method to measure the relative transmissibility (“transmission fitness”) of one strain of a pathogen compared to another. The model is applied to data from “competitive mixtures” experiments in which animals are co-infected with a mixture of two strains. We observe the mixture in each a...
Autores principales: | McCaw, James M., Arinaminpathy, Nimalan, Hurt, Aeron C., McVernon, Jodie, McLean, Angela R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084214/ https://www.ncbi.nlm.nih.gov/pubmed/21552544 http://dx.doi.org/10.1371/journal.pcbi.1002026 |
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