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How Much Remains Undetected? Probability of Molecular Detection of Human Plasmodia in the Field

BACKGROUND: In malaria endemic areas, most people are simultaneously infected with different parasite clones. Detection of individual clones is hampered when their densities fluctuate around the detection limit and, in case of P. falciparum, by sequestration during part of their life cycle. This has...

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Detalles Bibliográficos
Autores principales: Koepfli, Cristian, Schoepflin, Sonja, Bretscher, Michael, Lin, Enmoore, Kiniboro, Benson, Zimmerman, Peter A., Siba, Peter, Smith, Thomas A., Mueller, Ivo, Felger, Ingrid
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084249/
https://www.ncbi.nlm.nih.gov/pubmed/21552561
http://dx.doi.org/10.1371/journal.pone.0019010