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Intramyocardial Transplantation of Undifferentiated Rat Induced Pluripotent Stem Cells Causes Tumorigenesis in the Heart

BACKGROUND: Induced pluripotent stem cells (iPSCs) are a novel candidate for use in cardiac stem cell therapy. However, their intrinsic tumorigenicity requires further investigation prior to use in a clinical setting. In this study we investigated whether undifferentiated iPSCs are tumorigenic after...

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Detalles Bibliográficos
Autores principales: Zhang, Yuzhen, Wang, Dan, Chen, Minglong, Yang, Bing, Zhang, Fengxiang, Cao, Kejiang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084251/
https://www.ncbi.nlm.nih.gov/pubmed/21552563
http://dx.doi.org/10.1371/journal.pone.0019012