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GPVI and GPIbα Mediate Staphylococcal Superantigen-Like Protein 5 (SSL5) Induced Platelet Activation and Direct toward Glycans as Potential Inhibitors

BACKGROUND: Staphylococcus aureus (S. aureus) is a common pathogen capable of causing life-threatening infections. Staphylococcal superantigen-like protein 5 (SSL5) has recently been shown to bind to platelet glycoproteins and induce platelet activation. This study investigates further the interacti...

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Detalles Bibliográficos
Autores principales: Hu, Houyuan, Armstrong, Paul C. J., Khalil, Elie, Chen, Yung-Chih, Straub, Andreas, Li, Min, Soosairajah, Juliana, Hagemeyer, Christoph E., Bassler, Nicole, Huang, Dexing, Ahrens, Ingo, Krippner, Guy, Gardiner, Elizabeth, Peter, Karlheinz
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084272/
https://www.ncbi.nlm.nih.gov/pubmed/21552524
http://dx.doi.org/10.1371/journal.pone.0019190