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αA-Crystallin Peptide (66) SDRDKFVIFLDVKHF (80) Accumulating in Aging Lens Impairs the Function of α-Crystallin and Induces Lens Protein Aggregation
BACKGROUND: The eye lens is composed of fiber cells that are filled with α-, β- and γ-crystallins. The primary function of crystallins is to maintain the clarity of the lens through ordered interactions as well as through the chaperone-like function of α-crystallin. With aging, the chaperone functio...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084282/ https://www.ncbi.nlm.nih.gov/pubmed/21552534 http://dx.doi.org/10.1371/journal.pone.0019291 |