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Structural Basis for Variant-Specific Neuroligin-Binding by α-Neurexin

Neurexins (Nrxs) are presynaptic membrane proteins with a single membrane-spanning domain that mediate asymmetric trans-synaptic cell adhesion by binding to their postsynaptic receptor neuroligins. α-Nrx has a large extracellular region comprised of multiple copies of laminin, neurexin, sex-hormone-...

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Detalles Bibliográficos
Autores principales: Tanaka, Hiroki, Nogi, Terukazu, Yasui, Norihisa, Iwasaki, Kenji, Takagi, Junichi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084293/
https://www.ncbi.nlm.nih.gov/pubmed/21552542
http://dx.doi.org/10.1371/journal.pone.0019411