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Development and optimization of solid lipid nanoparticle formulation for ophthalmic delivery of chloramphenicol using a Box-Behnken design

The purpose of the present study was to optimize a solid lipid nanoparticle (SLN) of chloramphenicol by investigating the relationship between design factors and experimental data using response surface methodology. A Box-Behnken design was constructed using solid lipid (X(1)), surfactant (X(2)), an...

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Detalles Bibliográficos
Autores principales: Hao, Jifu, Fang, Xinsheng, Zhou, Yanfang, Wang, Jianzhu, Guo, Fengguang, Li, Fei, Peng, Xinsheng
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084315/
https://www.ncbi.nlm.nih.gov/pubmed/21556343
http://dx.doi.org/10.2147/IJN.S17386