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RAC3 is a promigratory co-activator of ERα

ERα is a ligand-dependent nuclear receptor that is important in breast cancer genesis, behavior and response to hormone-based therapies. A T7 phage display screen against full-length human ERα, coupled with genome-wide exon arrays, was used to identify RAC3 as a putative ERα co-regulator. RAC3 is a...

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Detalles Bibliográficos
Autores principales: Walker, Matthew P, Zhang, Maomao, Le, Thien P, Wu, Patricia, Lainé, Muriel, Greene, Geoffrey L
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084334/
https://www.ncbi.nlm.nih.gov/pubmed/21217774
http://dx.doi.org/10.1038/onc.2010.583