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c-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase

The progression and negative outcome of a variety of human carcinomas is intimately associated with aberrant activity of the c-Met oncogene. The underlying cause of this dysregulation, however, remains a subject of discussion, as the majority of cancer patients do not present with activating mutatio...

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Detalles Bibliográficos
Autores principales: Szabo, Roman, Rasmussen, Amber L., Moyer, Amanda B., Kosa, Peter, Schafer, Jeffrey M., Molinolo, Alfredo A., Gutkind, J. Silvio, Bugge, Thomas H.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084339/
https://www.ncbi.nlm.nih.gov/pubmed/21217780
http://dx.doi.org/10.1038/onc.2010.586