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Molecular insight into human platelet antigens: structural and evolutionary conservation analyses offer new perspective to immunogenic disorders
BACKGROUND: Human platelet antigens (HPAs) are polymorphisms in platelet membrane glycoproteins (GPs) that can stimulate production of alloantibodies once exposed to foreign platelets (PLTs) with different HPAs. These antibodies can cause neonatal alloimmune thrombocytopenia, posttransfusion purpura...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Blackwell Publishing Inc
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084503/ https://www.ncbi.nlm.nih.gov/pubmed/20804530 http://dx.doi.org/10.1111/j.1537-2995.2010.02862.x |