Programmable Sequence-Specific Transcriptional Regulation of Mammalian Genome Using Designer TAL Effectors

The ability to direct functional domains to specific DNA sequences is a long sought-after goal for studying and engineering biological processes. Transcription activator like effectors (TALEs) from Xanthomonas sp. present a promising platform for designing sequence-specific DNA binding proteins. Her...

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Detalles Bibliográficos
Autores principales: Zhang, Feng, Cong, Le, Lodato, Simona, Kosuri, Sriram, Church, George, Arlotta, Paola
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084533/
https://www.ncbi.nlm.nih.gov/pubmed/21248753
http://dx.doi.org/10.1038/nbt.1775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084533/
https://www.ncbi.nlm.nih.gov/pubmed/21248753
http://dx.doi.org/10.1038/nbt.1775

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