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Programmable Sequence-Specific Transcriptional Regulation of Mammalian Genome Using Designer TAL Effectors
The ability to direct functional domains to specific DNA sequences is a long sought-after goal for studying and engineering biological processes. Transcription activator like effectors (TALEs) from Xanthomonas sp. present a promising platform for designing sequence-specific DNA binding proteins. Her...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084533/ https://www.ncbi.nlm.nih.gov/pubmed/21248753 http://dx.doi.org/10.1038/nbt.1775 |