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Activation of the innate immune receptor Dectin-1 upon formation of a “phagocytic synapse”

Innate immune cells must be able to distinguish between direct binding to microbes and detection of components shed from the surface of microbes located at a distance. Dectin-1 is a pattern recognition receptor expressed by myeloid phagocytes (macrophages, dendritic cells and neutrophils) that detec...

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Detalles Bibliográficos
Autores principales: Goodridge, Helen S., Reyes, Christopher N., Becker, Courtney A., Katsumoto, Tamiko R., Ma, Jun, Wolf, Andrea J., Bose, Nandita, Chan, Anissa S. H., Magee, Andrew S., Danielson, Michael E., Weiss, Arthur, Vasilakos, John P., Underhill, David M.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084546/
https://www.ncbi.nlm.nih.gov/pubmed/21525931
http://dx.doi.org/10.1038/nature10071