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Activation of the innate immune receptor Dectin-1 upon formation of a “phagocytic synapse”
Innate immune cells must be able to distinguish between direct binding to microbes and detection of components shed from the surface of microbes located at a distance. Dectin-1 is a pattern recognition receptor expressed by myeloid phagocytes (macrophages, dendritic cells and neutrophils) that detec...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084546/ https://www.ncbi.nlm.nih.gov/pubmed/21525931 http://dx.doi.org/10.1038/nature10071 |