Cargando…
Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation
The canonical Wnt pathway plays an important role in the regulation of cell proliferation and differentiation. Activation of this signaling pathway causes disruption of the Axin/adenomatous polyposis coli/glycogen synthase kinase 3β complex, resulting in stabilization of β-catenin and its associatio...
Autores principales: | , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084683/ https://www.ncbi.nlm.nih.gov/pubmed/21411632 http://dx.doi.org/10.1091/mbc.E10-12-0985 |