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Human CD34(+) CD133(+) Hematopoietic Stem Cells Cultured with Growth Factors Including Angptl5 Efficiently Engraft Adult NOD-SCID Il2rγ(−/−) (NSG) Mice

Increasing demand for human hematopoietic stem cells (HSCs) in clinical and research applications necessitates expansion of HSCs in vitro. Before these cells can be used they must be carefully evaluated to assess their stem cell activity. Here, we expanded cord blood CD34(+) CD133(+) cells in a defi...

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Detalles Bibliográficos
Autores principales: Drake, Adam C., Khoury, Maroun, Leskov, Ilya, Iliopoulou, Bettina P., Fragoso, Maria, Lodish, Harvey, Chen, Jianzhu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084708/
https://www.ncbi.nlm.nih.gov/pubmed/21559522
http://dx.doi.org/10.1371/journal.pone.0018382