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Chromosome 15q25 (CHRNA3-CHRNA5) Variation Impacts Indirectly on Lung Cancer Risk

Genetic variants at the 15q25 CHRNA5-CHRNA3 locus have been shown to influence lung cancer risk however there is controversy as to whether variants have a direct carcinogenic effect on lung cancer risk or impact indirectly through smoking behavior. We have performed a detailed analysis of the 15q25...

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Detalles Bibliográficos
Autores principales: Wang, Yufei, Broderick, Peter, Matakidou, Athena, Eisen, Timothy, Houlston, Richard S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084737/
https://www.ncbi.nlm.nih.gov/pubmed/21559498
http://dx.doi.org/10.1371/journal.pone.0019085