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Preclinical Models for Neuroblastoma: Establishing a Baseline for Treatment

BACKGROUND: Preclinical models of pediatric cancers are essential for testing new chemotherapeutic combinations for clinical trials. The most widely used genetic model for preclinical testing of neuroblastoma is the TH-MYCN mouse. This neuroblastoma-prone mouse recapitulates many of the features of...

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Detalles Bibliográficos
Autores principales: Teitz, Tal, Stanke, Jennifer J., Federico, Sara, Bradley, Cori L., Brennan, Rachel, Zhang, Jiakun, Johnson, Melissa D., Sedlacik, Jan, Inoue, Madoka, Zhang, Ziwei M., Frase, Sharon, Rehg, Jerold E., Hillenbrand, Claudia M., Finkelstein, David, Calabrese, Christopher, Dyer, Michael A., Lahti, Jill M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084749/
https://www.ncbi.nlm.nih.gov/pubmed/21559450
http://dx.doi.org/10.1371/journal.pone.0019133