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Nocodazole Treatment Decreases Expression of Pluripotency Markers Nanog and Oct4 in Human Embryonic Stem Cells

Nocodazole is a known destabiliser of microtubule dynamics and arrests cell-cycle at the G2/M phase. In the context of the human embryonic stem cell (hESC) it is important to understand how this arrest influences the pluripotency of cells. Here we report for the first time the changes in the express...

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Detalles Bibliográficos
Autores principales: Kallas, Ade, Pook, Martin, Maimets, Martti, Zimmermann, Külli, Maimets, Toivo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084750/
https://www.ncbi.nlm.nih.gov/pubmed/21559451
http://dx.doi.org/10.1371/journal.pone.0019114