The Function of Hypoxia-Inducible Factor (HIF) Is Independent of the Endoplasmic Reticulum Protein OS-9

The protein “amplified in osteosarcoma-9” (OS-9) has been shown previously to interact with the prolyl hydroxylases PHD2 and PHD3. These enzymes initiate oxygen-dependent degradation of the α-subunit of hypoxia-inducible factor (HIF), a transcription factor that adapts cells to insufficient oxygen s...

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Detalles Bibliográficos
Autores principales: Brockmeier, Ulf, Platzek, Corinna, Schneider, Kirsten, Patak, Pauline, Bernardini, André, Fandrey, Joachim, Metzen, Eric
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084761/
https://www.ncbi.nlm.nih.gov/pubmed/21559462
http://dx.doi.org/10.1371/journal.pone.0019151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084761/
https://www.ncbi.nlm.nih.gov/pubmed/21559462
http://dx.doi.org/10.1371/journal.pone.0019151

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