Cargando…

The Function of Hypoxia-Inducible Factor (HIF) Is Independent of the Endoplasmic Reticulum Protein OS-9

The protein “amplified in osteosarcoma-9” (OS-9) has been shown previously to interact with the prolyl hydroxylases PHD2 and PHD3. These enzymes initiate oxygen-dependent degradation of the α-subunit of hypoxia-inducible factor (HIF), a transcription factor that adapts cells to insufficient oxygen s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brockmeier, Ulf, Platzek, Corinna, Schneider, Kirsten, Patak, Pauline, Bernardini, André, Fandrey, Joachim, Metzen, Eric
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084761/ https://www.ncbi.nlm.nih.gov/pubmed/21559462 http://dx.doi.org/10.1371/journal.pone.0019151

Ejemplares similares

Overcoming hypoxia-induced resistance of pancreatic and lung tumor cells by disrupting the PERK-NRF2-HIF-axis
por: Küper, Alina, et al.
Publicado: (2021)

The Importance of Hypoxia-Inducible Factors (HIF-1 and HIF-2) for the Pathophysiology of Inflammatory Bowel Disease
por: Kerber, Evelyn L., et al.
Publicado: (2020)

The ATP-binding cassette transporters ABCB1 and ABCC1 are not regulated by hypoxia in immortalised human brain microvascular endothelial cells
por: Patak, Pauline, et al.
Publicado: (2011)

Unraveling the function of Arabidopsis thaliana OS9 in the endoplasmic reticulum-associated degradation of glycoproteins
por: Hüttner, Silvia, et al.
Publicado: (2012)

Ways into Understanding HIF Inhibition
por: Schönberger, Tina, et al.
Publicado: (2021)

Synergistic Antitumor Effects of Endostar in Combination with Oxaliplatin via Inhibition of HIF and CXCR4 in the Colorectal Cell Line SW1116
por: Jin, Fengyan, et al.
Publicado: (2012)

Hypoxia, endoplasmic reticulum stress and chemoresistance: dangerous liaisons
por: Akman, Muhlis, et al.
Publicado: (2021)

The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia
por: Pompsch, Mosche, et al.
Publicado: (2018)

Depletion of HIF-1α by Inducible Cre/loxP Increases the Sensitivity of Cultured Murine Hepatocytes to Ionizing Radiation in Hypoxia
por: Hamidi, Akram, et al.
Publicado: (2022)

(H)IF applicable: promotion of neurogenesis by induced HIF-2 signalling after ischaemia
por: Leu, Tristan, et al.
Publicado: (2021)

Hypoxia-inducible factor 1α is Essential for Macrophage-mediated Erythroblast Proliferation in Acute Friend Retrovirus Infection
por: Schreiber, Timm, et al.
Publicado: (2017)

THE ENDOPLASMIC RETICULUM
por: Palade, George E.
Publicado: (1956)

OsHrd3 is necessary for maintaining the quality of endoplasmic reticulum-derived protein bodies in rice endosperm
por: Ohta, Masaru, et al.
Publicado: (2015)

Dendritic Cells under Hypoxia: How Oxygen Shortage Affects the Linkage between Innate and Adaptive Immunity
por: Winning, Sandra, et al.
Publicado: (2016)

Golgi clusters and vesicles mediate mitotic inheritance independently of the endoplasmic reticulum
por: Jokitalo, Eija, et al.
Publicado: (2001)

Mitofusin-2 Independent Juxtaposition of Endoplasmic Reticulum and Mitochondria: An Ultrastructural Study
por: Cosson, Pierre, et al.
Publicado: (2012)

Depletion of the thiol oxidoreductase ERp57 in tumor cells inhibits proliferation and increases sensitivity to ionizing radiation and chemotherapeutics
por: Hussmann, Melanie, et al.
Publicado: (2015)

Tumor cells rely on the thiol oxidoreductase PDI for PERK signaling in order to survive ER stress
por: Kranz, Philip, et al.
Publicado: (2020)

Hypoxia regulates adipose mesenchymal stem cells proliferation, migration, and nucleus pulposus-like differentiation by regulating endoplasmic reticulum stress via the HIF-1α pathway
por: Wu, Jianxin, et al.
Publicado: (2023)

Construction of the endoplasmic reticulum
Publicado: (1989)

Hypoxia-induced endoplasmic reticulum stress characterizes a necrotic phenotype of pancreatic cancer
por: Kong, Bo, et al.
Publicado: (2015)

Intermittent Hypoxia Induces Autophagy to Protect Cardiomyocytes From Endoplasmic Reticulum Stress and Apoptosis
por: Chang, Jui-Chih, et al.
Publicado: (2019)

H(2)S attenuates endoplasmic reticulum stress in hypoxia-induced pulmonary artery hypertension
por: Wu, Jianjun, et al.
Publicado: (2019)

Mitochondrial Dynamics, Mitophagy, and Mitochondria–Endoplasmic Reticulum Contact Sites Crosstalk Under Hypoxia
por: Wang, Shuying, et al.
Publicado: (2022)

Elucidating the Morphology of the Endoplasmic Reticulum: Puzzles and Perspectives
por: Lipowsky, Reinhard, et al.
Publicado: (2023)

Cytokine-Induced β-Cell Death Is Independent of Endoplasmic Reticulum Stress Signaling
por: Åkerfeldt, Mia C., et al.
Publicado: (2008)

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response
por: Schuck, Sebastian, et al.
Publicado: (2009)

Role of endoplasmic reticulum oxidase 1α in H9C2 cardiomyocytes following hypoxia/reoxygenation injury
por: Lai, Lina, et al.
Publicado: (2020)

Autophagy and Endoplasmic Reticulum Stress during Onset and Progression of Arrhythmogenic Cardiomyopathy
por: Pitsch, Mark, et al.
Publicado: (2021)

Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum
por: Staudacher, Jonas J., et al.
Publicado: (2015)

Calreticulin Translocation Aggravates Endoplasmic Reticulum Stress-associated Apoptosis during Cardiomyocyte Hypoxia/Reoxygenation
por: Xu, Fei-Fei, et al.
Publicado: (2015)

Chronic Intermittent Hypobaric Hypoxia Improves Cardiac Function through Inhibition of Endoplasmic Reticulum Stress
por: Yuan, Fang, et al.
Publicado: (2017)

Hypoxia–Induced Cytotoxic Drug Resistance in Osteosarcoma Is Independent of HIF-1Alpha
por: Adamski, Jennifer, et al.
Publicado: (2013)

Overexpression of KLF4 Suppresses Pulmonary Fibrosis through the HIF-1α/Endoplasmic Reticulum Stress Signaling Pathway
por: Wei, Shanchen, et al.
Publicado: (2023)

Endoplasmic Reticulum Stress and Cancer
por: Yadav, Raj Kumar, et al.
Publicado: (2014)

Regulation of endoplasmic reticulum functions
por: Namba, Takushi
Publicado: (2015)

Endoplasmic reticulum stress and apoptosis
por: Faitova, Jitka, et al.
Publicado: (2006)

Autophagic degradation of the endoplasmic reticulum
por: NAKATOGAWA, Hitoshi
Publicado: (2020)

The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei
por: Iyer, Advaitha, et al.
Publicado: (2022)

In Vitro Formation of the Endoplasmic Reticulum Occurs Independently of Microtubules by a Controlled Fusion Reaction
por: Dreier, Lars, et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_jfpucf7vgtj7vg2njvt4srupg7