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Altered T Cell Memory and Effector Cell Development in Chronic Lymphatic Filarial Infection That Is Independent of Persistent Parasite Antigen

Chronic lymphatic filarial (LF) infection is associated with suppression of parasite-specific T cell responses that persist even following elimination of infection. While several mechanisms have been implicated in mediating this T cell specific downregulation, a role for alterations in the homeostas...

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Detalles Bibliográficos
Autores principales: Steel, Cathy, Nutman, Thomas B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084782/
https://www.ncbi.nlm.nih.gov/pubmed/21559422
http://dx.doi.org/10.1371/journal.pone.0019197